Fluconazole 200 mg/100 ml I.V. is a medicine that belongs to a group called antifungals. It is used to treat different types of infections caused by fungi and yeast. These infections can affect parts of the body like the mouth, throat, food pipe, lungs, bladder, private parts, and even the blood.

This medicine contains Fluconazole, which works by stopping the fungus or yeast from growing. It does this by blocking a chemical needed to build the protective layer (cell membrane) of the fungus. Without this layer, the fungus cannot survive or grow properly, so it gets destroyed or stops spreading.

Key Features of Fluconazole Solution for Injection intravenous 200mg/ 100ml :

Fluconazole 200 mg/100 ml I.V. is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), oesophagal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, Fluconazole 200 mg/100 ml I.V. is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. Fluconazole 200 mg/100 ml I.V. is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs. It works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation.

Indications for Fluconazole Solution for Injection intravenous 200mg/ 100ml:

Fluconazole IV 200mg/100ml is used for the treatment of serious fungal infections, particularly in hospitalized or immunocompromised patients. Common indications include:

• Candidemia (bloodstream infections caused by Candida species)

   

• Disseminated/Systemic Candidiasis
• Including peritonitis, endocarditis, and urinary tract infections caused by Candida
• Oropharyngeal and Esophageal Candidiasis (especially in patients unable to take oral medications)
• Cryptococcal Meningitis
• Particularly in HIV/AIDS patients or organ transplant recipients
• Prophylaxis of Fungal Infections
• In immunocompromised patients, such as those undergoing chemotherapy, radiotherapy, or bone marrow transplant
• Vaginal Candidiasis
• When oral treatment is not possible or rapid IV action is required
• Candiduria (Candida in urine)
• In complicated urinary tract infections, especially in ICU or catheterized patients 

Dosage & Administration

• Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
• If Fluconazole Infusion and certain other medications are taken at the same time, the effect of treatment may be affected.
• Fluconazole Infusion with food-Fluconazole Infusion can be used with or without food.

Precautions

Talk to your doctor, pharmacist or nurse before you are given Fluconazole Infusion if you are currently, or have previously had problems with your liver if you have AIDS or have an infection that affects your whole body. if you have heart disease if you receive warfarin or any other drug which prolongs blood coagulation. if you have kidney disease if you have a yeast infection called cryptococcosis if you have a fungal infection after travelling outside of Europe if the fungal infection does not improve, as alternative antifungal therapy may be needed.. if you develop signs of ‘adrenal insufficiency’ where the adrenal glands do not produce adequate amounts of certain steroid hormones such as cortisol (chronic, or long lasting fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain). If you have ever developed a severe skin rash or skin peeling, blistering and/or mouth sores after you have been given Fluconazole Infusion.

Serious skin reactions including drug reaction with eosinophilia and systemic symptoms (DRESS) have been reported in association with Fluconazole Infusion treatment, Fluconazole Infusion should be stopped and seek medical attention immediately if you notice any of the symptoms related to these serious skin reactions.

Side Effects

Pregnancy, breast-feeding and fertility

You should not be given Fluconazole infusion if you are pregnant, think you may be pregnant, are trying to become pregnant or breast-feeding, unless your doctor has told you so. If you become pregnant while taking this medicine or within 1 week of the most recent dose, contact your doctor.

Pregnancy Women of child-bearing potential should use reliable contraception during long-term treatment with Fluconazole Infusion. Fluconazole taken during the first or second trimester of pregnancy may increase the risk of miscarriage. Fluconazole taken during the first trimester may increase the risk of a baby being born with birth defects affecting the heart, bones and/or muscles. There have been reports of babies born with birth defects affecting the skull, ears, and bones of the thigh and elbow in women treated for three months or more with high doses (400-800 mg daily) of fluconazole for coccidioidomycosis. The link between fluconazole and these cases is not clear

Breast-feeding-Fluconazole enters breast milk so women are advised not to breast-feed their babies while on Fluconazole Infusion.

Fertility-There is no data regarding the effects of Fluconazole on the human fertility.

Driving and using machines

Occasionally dizziness or fits can occur in people taking fluconazole so care should be taken when driving or operating machinery.

Fluconazole Infusion contains Sodium chloride

Fluconazole Infusion contains sodium chloride (salt). The infusion contains 3.5mg of sodium per ml of infusion (a total of 88mg sodium in a 25ml bottle, 177mg sodium in a 50ml bottle, 354mg sodium in a 100ml bottle and 709mg sodium in a 200ml bottle). If you are on a low sodium (salt) diet tell your doctor, pharmacist or nurse before they give you Fluconazole Infusion. 

Possible side effects – Serious side effects. 

• If you notice any of the following symptoms, you should inform the doctor or nurse immediately and the infusion should be stopped: 

Uncommon: 

• Fits (convulsions). 
• Yellowing of the skin and eyes (jaundice) and liver abnormalities 

Rare: 

• Anaphylaxis (allergic reaction): Swollen face, lips, tongue or throat, difficulty swallowing, hives and difficulties breathing
• Severe skin reaction which causes the outer layer of skin to detach (Toxic epidermal necrolysis).
• Severe rashes that may involve blistering and peeling of the skin (Stevens-Johnson syndrome).
• Lesions or ulcers in the throat, mouth and skin due to changes in white blood cells Liver problems and toxicity, including liver failure and hepatitis. 

Common:

• • Headache
• Rash
• Feeling sick (nausea
• ) Being sick (vomiting)
• Stomach ache or pain.
• Diarrhoea
• Increase in the blood of substances produced by the liver called liver enzymes 

Storage

Store in cool and dark place below 30°C away from direct sunlight.

Keep away from the reach of children.

Why Choose Fluconazole Solution for Injection intravenous 200mg/ 100ml From Regen Global Pharma?

Broad-Spectrum Antifungal Action

Fluconazole is a trusted antifungal agent effective against a wide range of fungal infections, including:

• Candidemia and systemic candidiasis
• Cryptococcal meningitis
• Oropharyngeal and esophageal candidiasis
  Its intravenous form is especially useful for hospitalized or immunocompromised patients where oral treatment is not feasible.

Ready-to-Use IV Formulation

Regen Global Pharma offers Fluconazole 200mg/100ml as a pre-mixed solution, eliminating the need for dilution or compounding. This:

• Reduces preparation errors
• Ensures consistent dosing and sterility
• Enhances clinical convenience in emergency and critical care settings

Manufactured Under WHO-GMP Standards

Regen Global Pharma ensures:

• High purity APIs
• Sterile production environment
• Quality assurance at every step
  This results in safe, stable, and reliable IV antifungal therapy compliant with global standards.

Excellent Tissue Penetration & Bioavailability

Fluconazole in IV form maintains:

• High plasma concentrations
• Excellent penetration into CSF, peritoneal fluid, and body tissues
  This ensures effective treatment of deep-seated and systemic infections.

Flexible Dosing & Pharmacokinetics

• Once-daily dosing possible due to long half-life
• Adjusted easily for renal-impaired patients
• Predictable and linear pharmacokinetics, reducing dosing complications

 

Disclaimer: The information provided on this website is for informational purposes and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it.  

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